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UK researchers are responsible for compliance with the Human Medicines Regulations 2012 and Misuse of Drugs Regulations 2001 where applicable.

The PLS-5 provides a comprehensive assessment of children's receptive and expressive vocabulary and is administrated by a trained assessor ( The developmental status of each participant was measured using the Mullen Scales of Early Learning (MSEL) administered by a trained assessor and the Vineland Adaptive Behavior Scale, 2nd edition (VABS-II) completed by parent interview

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The complimentary microneedling accessory is optional and must be used according to its supplied directions