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Q: Can retatrutide cause rebound weight gain if stopped

Obesity is a major risk factor for gout because excess fat increases the production of uric acid and reduces its excretion by the kidneys

Hypothalamic GLP-1R Knockdown and Rapamycin Benchmarking In the second cohort, 18-month-old mice received hypothalamic adeno-associated virus (AAV) encoding short hairpin ribonucleic acid (shRNA) to knock down GLP-1R or a scramble control, then exenatide or PBS for 13 weeks