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Because you can't just throw a sort of set of generic lifestyle suggestions at people, but you really do need to be kind of more targeted about how to help this specific person fight that biological imperative

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Table I [i] PIO pioglitazone, GLP-1R glucagon-like peptide 1 receptor, SGLT2 sodium-glucose co-transporters 2, TOFO tofogliflozin, SUL sulfonylurea, MET metformin, DAPA dapagliflozin, EXE exenatide, NAFLD non-alcoholic fatty liver disease, T2D type 2 diabetes, A1C glycated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, -GT gamma-glutamyl transferase, MRI-PDFF MRI-proton density fat fraction, MRE-LSM MR elastography-liver stiffness, RCT randomized controlled trial, EDICT Efficacy and Durability of Initial Combination Therapy, CAP controlled attenuation parameter, LSM liver stiffness measurement, BMI body mass index

Zhang Y, Fan B-Y, Pang Y-L, Shen W-Y, Wang X, Zhao C-X, Li W-X, Liu C et al (2020) Neuroprotective effect of deferoxamine on erastininduced ferroptosis in primary cortical neurons