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Animals were grouped as following: normal control group, a neutron irradiated control group, a low-dose L 10 B-3 vesicles group with neutron irradiation (250 mg/kg), a low-dose Dox@vesicles group with neutron irradiation (250 mg/kg L 10 B-3 vesicles and 5 mg/kg Dox), a low-dose Dox@vesicles group without irradiation, a high-dose vesicles group with neutron irradiation (350 mg/kg), and a high-dose vesicles group without irradiation

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This means each disposable syringe would hold a one-time dose of Wegovy

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