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Pain relief and effectiveness may sometimes take time for the patient to notice the difference, however, it can last between 6 12 months and in some cases, years

Wong AD, Ye M, Levy AF, Rothstein JD, Bergles DE, Searson PC

Setting realistic goals: Define specific objectives (pain reduction, return to specific activities, healing verified on imaging) rather than vague "feel better." Understand realistic timeline (weeks for soft tissue, months for bone, months to years for cartilage) preventing premature disappointment

explicitly did not rule on causation Medical guidance: Acetaminophen remains the recommended OTC pain and fever medication in pregnancy per ACOG, AAP, SMFM

In the NeuroEndoMetabolic (NEM) stress response , your bodys natural way of fighting the effects of stress, six circuits comprised of three organs or systems each work in an inter-related fashion