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8 weeks later, the rats of the HFD group were intraperitoneally injected with 30 mg/kg of Streptozotocin (STZ, Sigma, St

These medications have a one-week half-life, meaning theyre most effective when taken every seven days

The quality of included studies was assessed using appropriate tools such as the Cochrane Collaboration's tool for assessing risk of bias in randomized trials or the Newcastle-Ottawa Scale for observational studies

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