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Moreover, in type 2 diabetes patients, SS-31 reduced ROS production and regulated endoplasmic reticulum stress and autophagy, as well as intracellular environmental homeostasis [40, 41]

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Other antioxidants like vitamin C or E dont bind NO with the same affinity, so they dont suppress enteric nervous system signaling to the same degree

When explaining how cannabis stimulates appetite (causing the infamous munchies), Huberman refers to how the brain experiences an anticipation of taste. It so happens that Hill is currently researching what cannabis does to appetite in the lab with rats and a vapor model chamber system he likens to a Cheech and Chong hot box. He says that while even rats that have just eaten become ravenous again when intoxicated, we cant yet say anything definitive about the mechanism responsible