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In an interview with People published earlier this year, Clarkson said she had lost weight by following the advice of her doctor

The primary endpoint was the percentage of patients achieving an A1C of less than 7%

This strategy represents a novel mechanistic avenue for senolysis, distinct from conventional apoptosis-based approaches, with emerging evidence showing that senescent macrophages can induce ferroptosis in skeletal muscle during osteoarthritis progression 78 (Fig

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