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doi: 10.3389/fcimb.2026.1781905 Received 06 January 2026 Revised 07 May 2026 Accepted 18 May 2026 Published 04 June 2026 Volume 16 - 2026 Edited by Fei Pan, ETH Zrich, Switzerland Reviewed by Zeeshan Ahmad, Wayne State University, United States Ying-hao Pei, Jiangsu Provincial Hospital of Traditional Chinese Medicine, China Updates Copyright 2026 Hou, Gao, Wang, Sun, Zhang, Tian, Yang, Chen, Lian and Fang

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10.1016/j.neuropharm.2019.107748 Neuropharmacology 191 Yildirim SimsirI.SoyaltinU

Therefore, a multitude of BPC 157 beneficial effects related to the NO-system presented proof of concept [11,29] that BPC 157 consistently counteracted the induced general dysregulation of the NO-system, uncontrolled NO increase, and free radical formation and finally counteracted the course leading to neurodegenerative diseases