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( K ) DPP4 activity, ( L ) soluble DPP4 concentration, ( M ) active GLP-1, ( N ) active GIP, ( O ) insulin, and ( P ) glucagon from the PV and CP 15 minutes after glucose bolus in Dpp4 EC+/+ ( n = 713) and Dpp4 EC/ ( n = 611) mice

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Targeting key inflammatory cytokines and pathways, such as IL-1, TNF-, and NF-B, is a primary strategy to mitigate liver damage and systemic inflammatory response syndrome [29-32]

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