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However, it's important to note that for pernicious anaemia or deficiency with neurological involvement, intramuscular hydroxocobalamin injections remain the first-line treatment in the UK, as recommended by NICE and the British Society for Haematology

So maybe that's a long way around saying, "I don't know if it's always diarrhea predominant." I, personally, in clinic, have seen it a lot where it's constipation

It also is nearly completely noncaloric

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GSH binds to PrfA at the broad tunnel between the N-terminal and C-terminal domains to make PrfA change conformation and become constitutive activation (Hall et al., 2016)