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Understanding the nano-bio interaction of polymeric nanoparticles at the cellular and organ levels is a crucial fundamental and prerequisite to develop efficient and safe products

It is reported that Leishmania and Toxoplasma gondii can suppress the production of inflammatory cytokines, chemokines, and the expression of costimulatory molecules in M via interference with MAPK, NFB, STAT3, or activation of STAT6-PPAR/ pathways, thus promoting M to differentiate towards anti-inflammatory M2 phenotype

In pernicious anemia, holotranscobalamin decreases whereas in dietary deficiency, holotranscobalamin will remain relatively stable while total serum B12 decreases