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Gao Y, et al

Source: The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis (2021) Methyl B12 as a syrup showed promising improvements in individuals with autism, most likely because it improved oxidative status

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Skeptics counter that those figures come from voluntary reporting rather than controlled trials, and that questions remain about immunogenicity, whether the body mounts an immune response to the peptide