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For a long time, the manifestation of depressive symptoms has been also associated with the deficits in neurotrophic factor action in the brain [51], especially highlighting the role of diminished brain-derived neurotrophic factor (BDNF) signaling as important for the pathogenesis of this mental disorder [52]

It was also observed in other members of Bifidobacterium that can control the expression of genes involved in the utilization of raffinose, sucrose, or oligofructose (111)