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Little or no induction of GSNOR was apparent, while among the GPX sequences, GPX5 , GPX6 , and GPX7 were most obviously responsive, although some variation was observed between the experiments, including the two cat2 datasets

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Its effect on total body fat, as opposed to visceral fat specifically, is also less pronounced than the GLP-1 class compounds

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The reduction of hypothalamic GHS-R gene expression might impair the action of ghrelin on GH release