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However, being such a new synthetic drug, this also means research is still developing, and many of its potential side effects and long-term effects are still unknown or being uncovered
When erastin and/or the iron compound ferlixit were used to induce ferroptosis in HEY, COV318, PEO4 and A2780CP ovarian cancer cell lines, it was found that erastin treatment was accompanied by NCOA4-mediated ferritin phagocytosis and mitochondrial dysfunction in HEY cells with high intracellular unstable iron pools (58)
Keep the product at a temperature between 5C and 25C
Despite the availability of such evidence, recent survey studies of physiotherapists have highlighted that while there is widespread awareness of general principles, there is a considerable lack of fidelity in the translation of the evidence to clinical practice 1,2
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