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[1] [2] These pens are designed to deliver precise doses without requiring unit calculations

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Aaron Kelly, co-director of the Center for Pediatric Obesity Medicine at the University of Minnesota, has noted: "Any off-label GLP-1 use in children under 12 should be treated as a single-patient investigational protocol with IRB-level documentation and monitoring intensity." No published case series or retrospective cohort study has described semaglutide use in children under 12 as of May 2026