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Cyclodextrin complexation, nanocarriers, polymeric micelles, phospholipid complexation, and nanocrystals have been used to enhance the solubility and bioavailability of luteolin via slowing of the degradation in the blood stream and demonstrating increased dissolution and bioactivity, largely in cancer models [173, 175,176,177,178,179,180,181,182]
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Each scanning session included a magnetization-prepared rapid acquisition gradient echo (MPRAGE) T1-weighted sequence with 1 mm in-plane resolution and 1 mm slice thickness and a diffusion spectrum imaging (DSI) sequence including 128 diffusion-weighted images with a maximum b -value of 8000 s/mm 2 and one b0 reference image