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A recent analysis using Mendelian randomization showed that genetically predicted homocysteine levels increased the odds of NAFLD.[ref] Related article: NAFLD genes Cardiovascular disease: To answer the question of whether a modestly elevated homocysteine level is causally associated with an increased risk of cardiovascular disease, researchers again used huge genetic data sets and Mendelian randomization to determine causality
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J Biol Chem 285:3725137262 Kissner R, Nauser T, Bugnon P, Lye PG, Koppenol WH (1997) Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis
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