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Semaglutide for Obesity (NEJM, 2025) Rodriguez et al

In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in patients treated with semaglutide 0.5 and 1 mg once weekly injections (3%) compared to placebo (1.8%)

Studies have shown that Ozempic can cause stomach paralysis in some patients due to its impact on GLP-1 receptors in the gastrointestinal system

This information is vital because it affects how they interpret any stomach pain or nausea you might report during your illness

The results confirmed a key challenge of GLP-1 receptor agonists: 33% of the weight loss induced by semaglutide monotherapy was attributed to a loss of lean mass