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A similar restoration of capillary diameter towards normal size is seen on administering adenosine after coronary ischaemia 8 , probably also due to activation of ATP-sensitive K + channels 48 , and giving adenosine or the ATP-sensitive K + channel opener nicorandil improves outcome in human percutaneous coronary angioplasty by preventing no-reflow and thus improving ventricular function 49,50,51

B-vitamins are generally safe but dosing must be justified clinically

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To view a copy of this licence, visit About this article Cite this article Macura, B., Kiecka, A