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When utilizing sonication methods for preparing injectable solutions, it is important to consider factors such as type of solvent, temperature and duration of exposure, power intensity, sample concentration, and size distribution of particles in order to optimize the efficacy and safety of these drugs prior to administration

Then, the incorporation of two larger lateral microchambers allowed the stretching of the membrane, mimicking the natural pressure driven stretching that occurs during inspiration ( Figure 3A )

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A syringe containing the medication is connected to an access port in the primary tubing and the medication is administered through the port