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175-178 Nevertheless, niacin has demonstrated antithrombotic effects, including inhibiting a coagulation cascade enzyme called factor VII, reducing fibrinogen levels, decreasing expression of tissue factor, suppressing plasminogen activator inhibitor-1 (an enzyme that inhibits fibrinolysis), lowering blood viscosity, and decreasing platelet aggregation

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Therefore, the increasing rates of obesity and related metabolic disorders are fueling the GLP-1 receptor agonist market growth

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They remain unlicensed for dermatological conditions and are not included in NICE or British Association of Dermatologists guidance for psoriasis management