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Some causes of B12 deficiency are: Pernicious Anemia Autoimmune Diseases Leaky Gut Syndrome Ulcerative Colitis, Crohns and Celiac Disease Small Intestinal Bacterial Overgrowth (SIBO) H Pylori Infection Prolonged Usage of Gastric Reflux meds Vegan and Vegetarian diets MTHFR gene mutations Bariatric Surgeries Excessive Alcohol Consumption B12 and the Methylation Cycle: Methylation is a critical process that happens trillions of times in every cell each minute
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EXTERNAL LINKING SUGGESTIONS National Institutes of Health (NIH) - NAD+ and Aging Research: PubMed Central - NNMT and NAD+ Metabolism Studies: American Society for Cell Biology - Metabolic Research: Society for the Study of Inborn Errors of Metabolism - Metabolic Disorders: The Gerontology Society of America - Aging Research:
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Individuals with methylation issues, such as those with MTHFR variants, might respond differently to NNMT inhibition
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