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Not for human consumption, medical, veterinary, or diagnostic use

Dehydration from gastrointestinal side effects such as nausea, vomiting, or diarrhea can contribute to feeling drained and physically depleted

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Bariatric surgery may be considered for individuals with BMI 40 kg/m (or 35 kg/m with significant comorbidities) who have not achieved adequate weight loss through non-surgical interventions

The agency's position, restated in its public guidance, is that "retatrutide and cagrilintide cannot be used in compounding under federal law" because they are investigational compounds not eligible under sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act [6][14][15]