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At the time of writing, phase II clinical trials are underway for some of these agents with negative results in INVOKE-2 trial (van Lengerich et al., 2023

Feature C of Criterion 2 (chronic pain and/or instability) cannot be counted towards a diagnosis of hEDS in this situation

Massive ex vivo expansion of human natural regulatory T cells (T regs) with minimal loss of in vivo functional activity

PPF is an umbrella term that can describe progressive lung scarring in many interstitial lung diseases

Generic: The cost of branded versions of semaglutide GLP-1 (such as Wegovy or Ozempic) may differ from generic alternatives, affecting the overall price