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The top dose produced 20.9% average weight loss over 72 weeks and 20.2% in a direct comparison with semaglutides 13.7%. Its second receptor, GIP, separates tirzepatide from approved single-receptor GLP-1 drugs and helps explain the larger population-level weight loss. That 20.9% came from participants averaging about 105 kg at a BMI of 38, most of whom were sedentary

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(2018) Ferroptosis: a novel anti-tumor action for cisplatin, Cancer Res

As we age, levels of both NAD+ and glutathione decline, leading to reduced cellular efficiency and increased vulnerability to damage (Braidy et al., 2019)

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