Long, Zeng, Shi, Tian, and Chen at West China Hospital of Sichuan University published a systematic review and meta-analysis in Free Radical Research in 2014, pooling data from 35 prospective studies involving 571,511 participants and 72,196 deaths
May relate to vasodilation effects
In a rat model of focal cerebral ischemia induced by a 90 min occlusion of the middle cerebral artery (MCAO), the researchers compared the effects of a five-day pretreatment with ceftriaxone (CEF) or NAC to those of ischemic and chemical preconditioning protocols
0.05 mg/kg once daily subcutaneously, indefinitely, with no titration
Zhao H, Zhu Y, Zhang J, Wu Y, Xiang X, Zhang Z, Li T, Liu L