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The Science: How the Three Peptides Work Together Retatrutide: The Triple Agonist Retatrutide (LY3437943) is a novel triple agonist peptide that simultaneously activates GLP-1, GIP, and glucagon receptors a first-in-class mechanism among research peptides

Levels of Parabacteroides distasonis are reportedly lower in individuals with NAFLD, and this bacterium can mitigate obesity and metabolic dysfunctions by modulating the production of UDCA and LCA (Wang et al., 2019)

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Therapies that address both sides of the energy-balance equation may produce greater and more durable weight loss