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With respect to the treatment of neurodegenerative diseases, the general pro-survival anti-apoptotic activity of HGF supports the use of HGF mimetics for treating neurodegenerative diseases including but not limited to Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS), etc
This modification protects them from degradation by amino peptidases and in many cases determines functionality of protein or peptide
PloS One 14 (9), e0221330 (2019)
To minimize any discomfort, practitioners often apply a topical numbing cream or use injectables that contain lidocaine, a mild anesthetic, to make the procedure more comfortable
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