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This metabolic dialogue extends to iron availability: pro-inflammatory signals alter the expression of iron import (e.g., transferrin receptor 1, TfR1) and storage (e.g., ferritin) proteins, creating an iron-rich environment that primes cells for ferroptosis

There is some evidence that they help patients lose weight, but the effects are difficult to disentangle from those of positive lifestyle changes that often accompany them

doi: 10.1038/srep43328 148 Eulenberg-GustavusCBahringSMaassPGLuftFCKettritzR

48 IlicS.DrmicD.FranjicS.KolencD.CoricM.BrcicL.et al (2011a)

When it comes to in-clinic treatments, like GHK-Cu injections, we're entering a grey area