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A person should consult a specialist in cardiology or seek emergency care immediately if they experience: Chest pain, pressure, or tightness accompanying palpitations Severe shortness of breath or difficulty breathing Dizziness, lightheadedness, or fainting episodes Palpitations lasting more than several minutes Frequent episodes that interfere with daily activities Rapid heart rate exceeding 100 beats per minute at rest A family history of heart disease, sudden cardiac death, or arrhythmias Understanding when to worry about heart palpitations also involves recognizing patterns

J Immunol 168(3):14051412

In addition, another study reported that both mechanical hyperalgesia and thermal hyperalgesia due to oxaliplatin can be reduced by the use of a higher dose of melatonin (20 mg/kg, i.p.) in rats [48]

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