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The peptide has a short half-life, so effects build with repeated dosing rather than a single injection (track decay with the Peptide Half-Life Tracker)

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Nat Med (2017) 23(7):85968.10.1038/nm.4358 188 QinJLiYCaiZLiSZhuJZhangFet alA metagenome-wide association study of gut microbiota in type 2 diabetes