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This practice introduces cross-contamination and stability risks

The inclusion of patients on diverse regimens, both preserved and preservative-free, supports the generalizability of the effects of the formulation across a representative spectrum of real-world therapy

One key pathway identified in females across both plasma and brain tissues was the cysteine and methionine metabolism pathway

In preclinical models, Dihexa has shown the ability to increase synaptic markers like synaptophysin, improve neuronal counts in the hippocampus, and restore spatial memory and learning capacity in cognitively impaired animals

Each group saw increases in plasma folate and decreases in homocysteine, suggesting that methylfolate behaves predictably