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Intracellular iron overload not only inhibits osteoblast function but also enhances osteoclast activity, thereby contributing to osteoporosis

doi: 10.1080/21655979.2021.2024394 77 XuY.LiQ.GeP.MaoH.YangC

Why does Basaglar cause weight gain while Ozempic causes weight loss

In the PWA model, GE suppressed hypothalamic expression of BCAP31, a pro-apoptotic protein, and promoted proteins associated with autophagy-critical processes for neuronal function and energy homeostasis

Through these additional endocrine affects, the synthetic GHS peptides also markedly increase appetite and weight gain, modulate cell proliferation and survival, are cardioprotective, affect heart performance and vascular resistance, are immuno-supportive and anti-arthritic, influence gastric acid secretion and motility, energy/glucose metabolism, as well as exocrine and endocrine pancreatic function