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For additional background on these emerging areas of study, see our discussion of amylin protein as a therapeutic target in Alzheimers disease

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The involvement of HSP70 has recently been confirmed through photo crosslinking experiments showing a direct interaction between HSC70 and KFERQ-like motifs, enabling CMA (Seike et al., 2024)

It should be mentioned, though, that the bulk of current studies is laboratory research or animal models animal clinical trials are still scarce