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Air bubbles in subcutaneous injections cannot cause air embolism as they are absorbed harmlessly by fatty tissue beneath the skin

Despite these encouraging results, amyloid-related imaging abnormalities (ARIA) remain a significant adverse effect of antibody-based therapies

Its increased metabolism results in the breakdown and elimination of fat from the body occurring at a faster rate

Companies have therefore been pursuing complementary mechanisms that can retain or enhance the weight loss of GLP-1R therapies while preserving lean mass and driving the majority of weight loss from fat mass

10.1038/s41392-021-00701-5 83 ZhangT.ChaboryE.BritanA.GrignardE.PitiotO.SaezF.et al (2008)