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This review explores the bidirectional relationship between sleep and redox metabolism through five key areas: (1) sleeps role in free radical regulation, (2) ROS as mediators of age-related sleep disturbances, (3) feedback loops between impaired sleep and brain metabolism, (4) sleep, redox, and aging in peripheral systems, and (5) therapeutic strategies to restore redox balance and improve aging outcomes
10.1016/j.cell.2017.02.031 Cell 5 BorodkinaA
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Oct-Dec 2020;32(4):312-317
Levine RI, Frederick WR, Rapoport SI
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