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"I had the biggest aha along with many people in that audience," Winfrey said, adding that she had been blaming herself for being overweight without realizing that she had a predisposition "that no amount of willpower is going to control." While she opted not to name the specific drug she takes, Winfrey admits that she uses the medication here and there

The starting dose is 1.5mg once daily, increasing to 4mg, 9mg and then 25mg, with a minimum of one month spent at each dose level 10

Treatment with semaglutide tablets 14 mg once daily for 26 weeks resulted in a statistically significant reduction in HbA1c compared to empagliflozin 25 mg once daily (see Table 5)

It is usually safe to switch from semaglutide to tirzepatide, and research shows that it might even help with weight loss

However, individual responses may vary, and different approaches can be made to lessen the symptoms