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The skin parameters were measured with PRIMOS CR 3D system for periorbital wrinkles and a corneometer for hydration and elasticity at 4, 8, or 12 weeks of treatment

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doi:10.1002/dmrr.2470 11

Practical Prediction Assessment: Sustained price inflation, drug spending and persistent workforce shortages converge to create structural cost escalation, driving employer medical costs upwards, widening rural-urban capacity gaps and forcing employers, payers and consumers to absorb costs through higher premiums and tighter utilization management