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to conduct a multicenter retrospective cohort study to assess the association of GLP-1RAs with the risk of intestinal obstruction compared with non-GLP-1RA anti-diabetic medications including SGLT2 inhibitors, metformin, sulfonylureas (SU), thiazolidinediones (TZDs), dipeptidyl peptidase-4 (DPP-4) inhibitors, and insulins, across follow-up periods of 1, 3, and 5 years

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Al tratarse de un suplemento natural , el riesgo de toxicidad es mnimo