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The effect of PregS on AMPA receptor-mediated miniature excitatory post-synaptic current (mEPSC) frequency is blocked by lanthanide 3+ , a non-selective TRP channel blocker (155), providing support for TRPM3 as a target for PregS modulation of glutamate release

doi: 10.1167/iovs.14-14873 188 LiaoC-YBarrowFVenkatesanNNakaoYMauerASFredricksonGet al

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Monotherapy Research Dosing: Phase 1 Research (Weeks 1-4): Starting Research Dose: 0.03mL (0.3mg) gave via subcutaneous injection once per week

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