Further, this pathology may be exacerbated by D2 downregulation, creating an inflammatory imbalance
Expression of GliT-GFP fusion protein completely restored gliotoxin resistance (10 g/ml), although colonies appeared white (Figure S9)
2005 Aug;37(8):468-73
This integrated approach has allowed us to determine the structural basis of GABA reuptake inhibition through the transporter GAT1, uncover the molecular mechanisms of inverse agonism at the kappa-opioid receptor, resolve the activation architecture of complement receptors C3aR and C5aR1, and capture nucleotide-release intermediates at the mu-opioid receptor work published in Nature, Nature Chemical Biology, Nature Communications, and Cell
On April 28, 2026, the FDA announced two successful proof-of-concept real-time trials in which sponsors report endpoints and data signals to the agency as they occur, instead of collecting, analyzing, and submitting data in batches