Additionally, ketamine activates the NLRP3 inflammasome, inducing caspase-1 activation and neuronal pyroptosis, further contributing to neuroinflammation in regions, such as the hippocampus and prefrontal cortex (Zhang et al., 2021)
Polycystic ovary syndrome (PCOS) Increased blood sugar leads to increased oxidative stress, which depletes glutathione in its attempts to combat this oxidative stress
For managing symptoms of severe itching in patients with cholestatic DILI, antihistamines like hydroxyzine or diphenhydramine, or bile acid resins like cholestyramine, can be helpful
Some practitioners monitor free T3, particularly in patients who report symptoms despite normal TSH and free T4 values
Common stacks include: CJC-1295/Ipamorelin for synergistic fat metabolism