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Importantly, treatment of DIO mice with our NNMT inhibitors did not impact food intake, but produced marked reductions in body weight, WAT mass, adipocyte size, and cholesterol levels with negligible toxicity or observable adverse effects

Who is it for Veterinarians, farmers, and pet owners who suspect their dogs, cats, calves, foals, cattle, or horses may have a vitamin B12 deficiency

Monitor the sitesome redness, soreness, or slight swelling is normal

In obesity and metabolic dysfunction, NNMT is often overexpressed in adipose tissue, depleting nicotinamide and lowering NAD+ availability [2]