18 She had previously been managed with metformin, pioglitazone, and insulin, then was started on liraglutide (0.6mg/day titrated to 1.2mg/day) in combination with metformin
While most HSCs lose autophagic capacity with age, a fraction maintains high autophagy and resembles young HSCs 37
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however, in the 8-month-old group, the litter size of S8/ Gss / males was significantly smaller than in the S8/Control males (Fig