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Recent research has demonstrated that the pathophysiology of IBD is largely influenced by T cell-mediated immune responses in the intestinal mucosa, specifically the imbalance in the dynamic equilibrium between Th17 and Treg cells, which is crucial for the onset and progression of IBD (179)

Astrocytes assemble Thalamocortical synapses by bridging NRX1alpha and NL1 via Hevin

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When blood comes into contact with the non-endothelial surface of the circuity, the conformation of FXII is altered, and a small amount of activated FXII(FXIIa) is produced, with circulating levels of FXIIa reaching a maximum within 10 mins of ECMO initiation (49)