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There isnt enough data to confirm that microdosing can help you live longer, says clinical pharmacist practitioner Anne Kom of the University of North Carolina Medical Center in Chapel Hill, who published a 2025 e-letter about microdosing GLP-1s in Diabetes Care

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Where the pharmacology is actually decided Whatever the brand on the box, GLP-1 receptor agonists such as semaglutide, liraglutide, and dulaglutide, along with the GIP/GLP-1 dual agonist tirzepatide, act on appetite signaling, satiety, and the rate at which the stomach empties

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