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Roles of L-asparaginase in cancer metabolism including asparagine depletion, apoptosis induction, autophagy and immunity are also detailed

The proper long-term storage method is refrigeration at 28C after opening, or controlled room temperature (2025C) for sealed unopened vials

A commonly used protocol involves administration five times per week for approximately eight weeks, followed by a two-week break before repeating the cycle, if appropriate

It is designed to help correct or prevent vitamin B deficiencies that may affect energy levels, nerve health, and red blood cell production

For TB-500, regulators said they could not find any human studies