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Figure 3 Elevated GPX4 and Ferrous Iron Are Potential Therapeutic Targets of CRC Persister Cells and Tumors The key event in ferroptosis is cell membrane damage associated with peroxidation of lipids ( GPX4 expression

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The American Journal of Clinical Nutrition;2011 Jul Kondala R Atkuri, John J Mantovani, Leonard A Herzenberg, Leonore A Herzenberg

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Contrastingly, poly- and mono-unsaturated fatty acids such as arachidonic acid, linolenic acid, or alpha-linolenic acid decreased in their intracellular abundance when albumin was present (Fig